Archfiend of the Dross + Heartless Act + Jon Irenicus, Shattered One…

€ 0,47
Archfiend of the Dross
Creature — Phyrexian Demon
€ 0,13
Heartless Act
Instant
€ 0,19
Jon Irenicus, Shattered One
Legendary Creature — Elf Wizard

Result

Target opponent loses the game at the beginning of their next upkeep

Combo data from Commander Spellbook.